Research Papers of AJBPR

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Volume : 1 | Issue : 1

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Dissolution Testing of Formulations: A Regulatory, Industry and Academic Perspective

Sachin Kumar Singh,Dev Prakash and K.K. Srinivasan
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Removal of Heavy Metals from Highway Run off Using Agricultural Waste Wheat Bran

Kishor Kumar Singh, Upasana Singh, Bhanu Pratap Singh and Abhimanyu Yadav
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Wheat bran is a low cost biosorbent that has been used for the removal of heavy metal ions from highway runoff. It is noted that increase in Pb2+ concentration and pH, caused the increase in adsorption capacity of wheat bran. In relation to this, a decrease in wheat bran dose results in a higher metal loading on the wheat bran. The adsorption data fitted the Langmuir and Freundlich model. In this investigation, order of heavy metal removal by wheat bran is Pb2+ > Cu2+ > Zn2+. A high concentration of co-existing ions such as Ca2+ and Mg2+ depresses the adsorption of heavy metal. Dissolved organic matter (DOM) has a significant influence on metal adsorption. In column studies, a long breakthrough time is observed for heavy metals according to the ion selectivity on wheat bran. The metal adsorption capacity per wheat bran mass is found more in batch studiesthan in column studies. Flushing of the column saturated with heavy metals by 0.1M CaCl2 solution results in the elution of a highly concentrated metal within shortened pore volumes, indicating that wheat bran repeatedlybe utilized for the treatment of heavy metals.

Simultaneous Estimation and Validation of Aceclofenac and Paracetamol from bulk and Tablets Using Mixed Hydrotropic Solubilisation

S.N.Anish Vinnakota, R.Deveswaran, V.Jhansipriya Marabathuni, S.Bharath, B.V.Basavaraj and V.Madhavan
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Hydrotropy is the term that has been used to designate the increase in aqueous solubility of poorly water-soluble compounds in hydrotropic solutions. In the present investigation mixed hydrotropicsolubilization phenomenon was employed in simultaneous estimation of solubilize poorly water-soluble drugs aceclofenac and paracetamol from bulk powder and its tablet dosage form. Aceclofenac showed maximum absorbance at 274.5 nm, whereas paracetamol showed maximum absorbance at 261.5 nm. Thesolubility of both aceclofenac and paracetamol was enhanced to greater extent in mixed hydrotropic solution of 30% urea with 20% sodium citrate. Both the drugs showed linearity in the concentration range
of 5-40 μg/mL and 4-40 μg/mL. Both the drugs showed good regression values of 0.9955 for aceclofenac and 0.9943 for paracetamol at their respective wave lengths. The estimated label claim was found to be 102.43±0.264 mg for aceclofenac and 99.28±0.681 for paracetamol with less standard deviation. The
results of recovery study revealed that any small change in the drug concentration in the solution could be accurately determined by the proposed method. The value of LOD and LOQ was found to be 0.2129 μg/ml and 0.6451μg/ml for aceclofenac and 0.2735 μg/mL and 0.8290 μg/mL that indicated good sensitivity of proposed method. The proposed method explains a new, simple, cost effective, accurate, and precise simultaneous estimation of aceclofenac and paracetamol using the mixed hydrotropic solubilization phenomenon that can be successfully adopted for routine analysis of aceclofenac and paracetamol in tablet dosage form.

One-pot Synthesis of Fluorescent 4-Amino-naphthalimide Dyes in Dioxane

Ghasem R. Bardajee
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Microwave Assisted Solid Support Synthesis of Some 2, 4-Dihydroxy Substituted Chalcones as Potential Antibacterial Agents

Sheetal Shakhawat, Anju Devpura, Parul Tiwari and Shiv Singh Dulawat
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Use of Cadmium Sulphide as Photocatalyst in Solar Desalination

Manisha Sindal, Shobha Rastogi and Ajay Sharma
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Synthesis and Characterization of Some lanthanide series (La+3, Pr+3, Nd+3, Sm+3 , Gd+3) Metal ion Complexes with Acid Orange – 7 (Ligand)

Jignesh A. Patel, N.K. Prajapati, Janki Vyas and Asha D.Patel.
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Pharmacognostical and Physico-chemical Standardization of Leaves of Sida acuta

Carol P. Macwan, A. J. Patel, M. A. Patel, K. R.Chauhan and R. P. Solanki
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Screening and Temperature Optimization for Lipase-Producing Bacteria from Waste Contaminated Water

Mishra Ankit, Sunil K Yaginik, Mishra Pranali, Yadav Sahdev K
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Spectrophotometric Determination of Nitrazepam and Nimodipine in pure and the Tablet Dosage Forms

Hosakere D. Revanasiddappa, Shiramahally M. Mallegowda, Hemavathi N. Deepakumari and Kanakapura B. Vinay
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Hydraulic Conductivity of Na, NH4 and their Different types of soil Mixture with Distilled Water

Ganpat R. Patel, Asha D. Patel and N. K.Prajapati
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Synthesis and Antimicrobial Study of 4-Benzylidene-2-phenyl-1-(5-phenylthiazole-2-yl)-1H-imidazol-5(4H)-one

Kumudini Bhanat, Narendra Parashar, Khusboo Jain and.V.K.Sharma
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Synthesis of Several 2-(1-Pyrrolidinyl)-4, 6-Diarylpyrimidines Under Microwave Irradiation on Inorganic Solid Support and their Antibacterial Activity

Anju Devpura, sheetal Shakawat ,Smmer S Chudawat,Jayant P sing ,Parual Tiwari and Shiv Singh Dulawat
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Effects of Bioinoculants on Quality Seedlings Production of Delonix Regia in Tropical Nursery Conditions

M. Meenakshisundaram, K. Santhaguru And K. Rajenderan.
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Synthesis and Antimicrobial Activity of Some New N-(3-(4-chloro phenyl)-1-phenyl- 1H-pyrazol-4-yl) methylene)-4H-1, 2, 4-triazol-4-amine Derivatives

Jabali J. Vora, Dinesh R. Patel , Akash R. Patel and Yamini S. Patel
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synthesis and antimicrobial activity of some 4 - oxo – thiazolidines-5- acetic acids.

M. Chatrabhuji, K. B. Vyas, K. S. Nimavat and N. K. Undavia
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Niosomes as a Potential Carrier for Controlled Release of Cefuroxime Axetil

S.Sambhakar, B. Singh, S. K. Paliwal and P.R.Mishra
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Microwave Assisted Synthesis of 4-(substituted benzylidene)-1- (5-mercapto-1, 3, 4-thiadiazol-2-yl) -2-phenyl-1H-imidazol-5(4H)-one

Sudhir Bharadwaj, Khushboo Jain, Bharat Parashar, G.D.Gupta and V. K. Sharma
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Analytical Method Development And Method Validation Of Tiotropium Bromide And Formoterol Fumarate Metered Dose Inhaler(Mdi) By Using Rp-Hplc Method

B.D Shah, S. Kumar, Y. C. Yadav, A.K. Seth, T. K. Ghelani, G. J. Deshmukh
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Spectrophotometeric Analytical Method of Nutraceutical Scopol

Anuj Malik, Ashok Kushnoor, Vipin Saini, Sarita Singhal, Sharad Kumar, Yogesh Chand Yadav
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Formulation and Evaluation of Timolol Maleate Ocular Insert

T.K. Ghelani, A. K. Seth, V. Saini, S. Singhal, S. Kumar1, Y. C. Yadav
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Physico-chemical and Pesticide analysis of River Ganga in Allahabad City, Uttar Pradesh, India

Divya Raghuvanshi, Ruby Pandey, Vikash Pandey, Pramod Kumar Sharma & D. N. Shukla
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