Current Research Papers of ACTAVELIT - Volume : 4 and Issue : 1

Influence of Some Safely Additives on Precipitation of Gypsum in Sodium Chloride Solution and Two Alloys

Samia K. Hamdona, Mona Fathi El-Naggar & Omayma H.Abd El-Hamid

The effect of some additives on the precipitation of gypsum in 0.7 mol l-1 sodium chloride solutions and two alloys (Brass –SS) was investigated in the present work. The degree of inhibition was estimated from measurements of the calcium ion and from specific solution conductivity measurements in the supersaturated solutions during the course of the precipitation process. The order of the degree of inhibition is Yeast > Ferulic acid (FA ) > Tyrosine > Histidine > Glutamic acid. The effect of FA and Yeast on the crystals of gypsum scales morphology and structures were examined through scanning electron microscopic (SEM) and X ray diffraction studies (XRD). The results show that the FA and yeast acts as a very good safely antiscaling inhibitor for gypsum.

Method validation and migration study of shellac in the peel and pulp of orange

Ved Prakash, Ajay Kumar Shandil, M.L. Aggarwal, K. M. Chacko

India is one of the largest producer of shellac in the world. The shellac coating have been carried out on the surface of oranges fruits. The migration study of shellac (Butolic acid) from orange surface to the peel and pulp of orange have been performed and a method validation for Butolic acid (an ingredient of Shellac) was carried out with the help of Liquid Chromatography- Mass Spectroscopy (LC-MS/MS). The extraction of shellac from the peel and pulp of oranges have been carried out by QuEChERS method using ethyl acetate as a solvent. The method validation study was performed for Specificity, Linearity, Repeatability, Limit of Detection (LOD), Limit of Quantification (LOQ), Recovery, Ruggedness, Matrix effect and Robustness. The mass spectrometry parameter was optimized in Multi-Reaction Monitoring (MRM) and negative Electrospray Ionization (ESI) mode.  The migration behavior of Shellac from peel surface to internal peel and pulp have been studied for 0 day to 30 days’ time periods and it was observed that the absorbed concentration of shellac in the peel was higher in compare to pulp. The absorbed concentration of shellac in peel and pulp was increased with time. 

Synthesis of Novel Substituted 3-(Phenyl Sulfanyl)-5-(Pyridin-3-Yl)-4h-[1, 2, 4] Triazol-4-Amine Derivatives and Evaluation of their Antimicrobial Screening

S. R. Kane, S. K. Mohite and S. V. Jawarkar

Heterocyclic nucleus played a vital role in the development of different medicinal agents and in the field of agrochemicals. This nucleus is present in many products such as drugs, vitamins, food, flavorings, plant dyes, adhesives and herbicides. It is seen from the current literature that pyridine congeners are associated with different biological properties like pesticide, insecticides and fungicidal activity. These reports encouraged us to plan for modification of 1, 2, 4-triazole into various bioactive structures and their subsequent evaluation for biological activity. So present study deals with synthesis and study of antimicrobial activity

Evaluation of antibacterial and antifungal activity of methanolic and ethanolic extracts of the leaves Azadirachta indica against clinical isolates

O. Gangarani Devi, T. Chand Singh, O. Ibeton Devi, E. Jadu Singh & Kh.Ujala Devi

Plants have been a source of herbal remedies throughout the history of mankind. Various medicinal plants have been used for years in daily life to treat diseases all over the world. In the present study, antimicrobial activity of Azadirachta indica was evaluated against pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella typhi, Salmonella paratyphi A, Salmonella paratyphi B) and fungi (Aspergillus niger, Penicillium species, Fusarium species and Candida albicans).  All the test organisms were screened for their antimicrobial activity against leaf extract of A. indica by agar well diffusion method. The methanolic extract of leaves of Azadirachta indica was found extremely effective against Staphylococcus aureus, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella paratyphi A and Salmonella typhi. The ethanolic extract of leaves of Azadirachta indica was found to be effective against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. The methanolic extract of leaves of Azadirachta indica was found extremely effective against Penicillium species and Aspergillus niger and resistant to Fusarium species and Candida albicans. The ethanolic extract of leaves of Azadirachta indica showed effective against Aspergillus niger, Penicillium species and Fusarium species and resistant to Candida albicans.

Correlation of Iron Binding Stores with Cardio metabolic risks in Obesity and Type 2 Diabetes Mellitus in Egyptian population.

Lamiaa A. A. Barakat , I.M. El-deen, Hassan A. Shora, El -Sayed Abd El-Samee, Taher Abdel Aziz

Purpose: Elevated body iron stores could promote oxidative stress, and in this manner affects the pathogenesis of insulin resistance. In this study, we investigated the relationship between body iron stores represented in serum ferritin and transferrin saturation together with insulin resistance and other cardio metabolic risk factors. Material and methods: In Egyptian subjects, we measured fasting serum ferritin and Transferrin saturation (TR %) was calculated with the formula: (Serum iron level X 100) / total iron-binding capacity in one hundred sixty five Egyptian subjects divided as controls, obese and obese diabetics. Body mass index (BMI), waist circumference (WC) and blood pressure were measured in all subjects. Insulin resistance was assessed using the homeostasis model assessment for insulin resistance (HOMA-IR). All subjects were investigated to analyse the change in their total cholesterol, HDL-C, non-HDL-C, and triglycerides levels. Results: Serum ferritin was significantly higher (p<0.05) in diabetic compared with non-diabetic subjects, serum ferritin also higher in obese non diabetics compared to non-obese controls. However, this difference did not reach the level of significance. There was non-significant difference in transferrin saturation (TR %) among studied groups. Significant positive correlation was seen between serum ferritin & BMI, WC and diastolic blood pressure, significant negative correlation between it & HDL-C and non-significant positive correlation with systolic blood pressure, fasting blood glucose, Hb A1C and non-HDL-C. Conclusion: serum ferritin associated with diabetes mellitus and cardio metabolic risk factors, while transferrin saturation did not.